Found 20 matching trials
Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)
PHASE1This clinical trial studies the safety, tolerability, and pharmacology of a...
Location
Barnes Jewish Hospital- Washington University School of Medicine
Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)
PHASE2This clinical trial was conducted to study hypophosphatasia (HPP), a bone d...
Location
Shriner's Hospital for Children
Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease
PHASE4The study will evaluate safety, tolerability, efficacy, pharmacokinetics, a...
Location
Multiple Locations
Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan
PHASE4This is a multicenter study in Japan. Eleven sites which have already parti...
Location
Multiple Locations
Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa
PHASE3The primary objective of this study is to assess the efficacy of ALXN1850 v...
Status
Active Not Recruiting
Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)
PHASE2This clinical trial studies the long term safety and efficacy of asfotase a...
Location
Shriners Hospital for Children
Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)
N/AThis clinical trial is being conducted in Hypophosphatasia, a bone disorder...
Status
Approved For Marketing
Location
Colorado Center for Bone Research
Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP
PHASE3The primary purpose of this study is to evaluate the efficacy of ALXN1850 v...
Status
Active Not Recruiting
Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)
PHASE1This clinical trial studies the safety and efficacy of asfotase alfa in inf...
Location
Arkansas Children's Hospital
Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia
PHASE4The primary objective of this study is to evaluate the effect of immunosupp...
Location
Multiple Locations